High Accuracy, Low Blood Volume Microarray-Based Test For Bacterial Sepsis
The Silent Killer. The killer in question is a condition called sepsis. Sepsis arises when the body’s immune system response to infection goes out of control and it attacks its own tissues and organs.
The results can be devastating – sepsis results in more fatalities in the UK each year than bowel, breast and prostate cancer combined, yet relatively few people are aware of it. To help face this challenge, research at the University, has led to the development of an effective new test for sepsis. The test works by measuring a specific set of genetic markers in patients. It is fast, sensitive, specific and works by removing false negative results associated with current gold standard microbiological methods.
Bioinformatic Method To Enhance Gene Expression And Improve Recombinant Vaccines
Flu, or influenza, is an all too familiar example of an infectious disease that is caused by an RNA virus – with forms that affect various species; notably humans, birds and pigs.
There are a range of other well-known RNA viruses, including Hepatitis C, measles, ebola and SARS. Extensive research undertaken at the Roslin Institute (Part of the College of Medicine and Veterinary Medicine of the University of Edinburgh) into the evolution and pervasion of such RNA viruses led to an unexpected discovery. As a result a new technology innovation which has significant potential as a platform for vaccine and vector design.
A new technology that consists of 12 K. pneumoniae strains, genetically engineered to carry mutations known to be implicated in the development of drug resistance including antimicrobial efflux, virulence, transcription factor regulation and membrane stability. An instrumental set of strains for use in antibiotic drug discovery and screening.
Detection of operational position during endoscopy is not currently a standard feature; however, it has been shown to provide advantages during endoscope insertion.
A current method uses electromagnetic coils on the endoscope guide, but this cannot give the position of the fibre itself, which often extends beyond the guide. In some cases, a guide is not used, and therefore positioning is done ‘by feel’ or by looking at the camera image.
A New method of detecting endoscope position has been developed at The University of Edinburgh. The method accurately determines the exact position of the end of the fibre of an endoscope during a procedure, by optically imaging through the body. This gives precise knowledge of the location of observed tissue abnormalities, and the ability to effectively sample multiple regions of an organ.
Find out more about this technology and how you can collaborate on further development of the technology for commercial use: http://edin.ac/2siGDsk